The Role of Water in Activation Mechanism of Human N-Formyl Peptide Receptor 1 (FPR1) Based on Molecular Dynamics Simulations

The Formyl Peptide Receptor 1 (FPR1) is an important chemotaxis receptor involved in various aspects of host defense and inflammatory processes. We constructed a model of FPR1 using as a novel template the chemokine receptor CXCR4 from the same branch of the phylogenetic tree of G-protein-coupled re...

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Detalles Bibliográficos
Autores principales: Yuan, Shuguang, Ghoshdastider, Umesh, Trzaskowski, Bartosz, Latek, Dorota, Debinski, Aleksander, Pulawski, Wojciech, Wu, Rongliang, Gerke, Volker, Filipek, Slawomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506623/
https://www.ncbi.nlm.nih.gov/pubmed/23189124
http://dx.doi.org/10.1371/journal.pone.0047114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506623/
https://www.ncbi.nlm.nih.gov/pubmed/23189124
http://dx.doi.org/10.1371/journal.pone.0047114

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