Sequence-Specific Inhibition of Small RNA Function

Hundreds of microRNAs (miRNAs) and endogenous small interfering RNAs (siRNAs) have been identified from both plants and animals, yet little is known about their biochemical modes of action or biological functions. Here we report that 2′-O-methyl oligonucleotides can act as irreversible, stoichiometr...

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Detalles Bibliográficos
Autores principales: Hutvágner, György, Simard, Martin J, Mello, Craig C, Zamore, Phillip D
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC350664/
https://www.ncbi.nlm.nih.gov/pubmed/15024405
http://dx.doi.org/10.1371/journal.pbio.0020098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC350664/
https://www.ncbi.nlm.nih.gov/pubmed/15024405
http://dx.doi.org/10.1371/journal.pbio.0020098

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