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Decrease in Proportion of CD19(+)CD24(hi)CD27(+) B Cells and Impairment of Their Suppressive Function in Graves’ Disease

IL-10-producing B cells (B10 cells) have been shown to play a suppressive role in the peripheral blood of humans, with their numbers and function altered in several autoimmune diseases. However, the role of B10 cells in Graves’ disease (GD) remains unknown. In this study, we demonstrated that B10 ce...

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Detalles Bibliográficos
Autores principales: Zha, Bingbing, Wang, Luman, Liu, Xiaoming, Liu, Jun, Chen, Zaoping, Xu, Jiong, Sheng, Li, Li, Yiming, Chu, Yiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506658/
https://www.ncbi.nlm.nih.gov/pubmed/23189166
http://dx.doi.org/10.1371/journal.pone.0049835