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The Peripheral Binding of 14-3-3γ to Membranes Involves Isoform-Specific Histidine Residues
Mammalian 14-3-3 protein scaffolds include seven conserved isoforms that bind numerous phosphorylated protein partners and regulate many cellular processes. Some 14-3-3-isoforms, notably γ, have elevated affinity for membranes, which might contribute to modulate the subcellular localization of the p...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506662/ https://www.ncbi.nlm.nih.gov/pubmed/23189152 http://dx.doi.org/10.1371/journal.pone.0049671 |