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The Peripheral Binding of 14-3-3γ to Membranes Involves Isoform-Specific Histidine Residues

Mammalian 14-3-3 protein scaffolds include seven conserved isoforms that bind numerous phosphorylated protein partners and regulate many cellular processes. Some 14-3-3-isoforms, notably γ, have elevated affinity for membranes, which might contribute to modulate the subcellular localization of the p...

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Detalles Bibliográficos
Autores principales: Bustad, Helene J., Skjaerven, Lars, Ying, Ming, Halskau, Øyvind, Baumann, Anne, Rodriguez-Larrea, David, Costas, Miguel, Underhaug, Jarl, Sanchez-Ruiz, Jose M., Martinez, Aurora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506662/
https://www.ncbi.nlm.nih.gov/pubmed/23189152
http://dx.doi.org/10.1371/journal.pone.0049671