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Early steps of microglial activation are directly affected by neuroprotectant FK506 in both in vitro inflammation and in rat model of stroke

Neuroprotective and/or neuroregenerative activity of FK506, its derivatives, and to a lesser extent cyclosporin A (CsA) in animal models of neurodegenerative diseases of different etiology have been reported. Here, we verified a hypothesis that the most likely mechanism of their neuroprotective acti...

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Detalles Bibliográficos
Autores principales: Zawadzka, Malgorzata, Dabrowski, Michal, Gozdz, Agata, Szadujkis, Barbara, Sliwa, Marcin, Lipko, Maciej, Kaminska, Bozena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506835/
https://www.ncbi.nlm.nih.gov/pubmed/22806180
http://dx.doi.org/10.1007/s00109-012-0925-9