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Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases

Scientific understanding of the genetic components of aging has increased in recent years, with several genes being identified as playing roles in the aging process and, potentially, longevity. In particular, genes encoding components of the nuclear lamina in eukaryotes have been increasingly well c...

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Detalles Bibliográficos
Autores principales: Zhavoronkov, Alex, Smit-McBride, Zeljka, Guinan, Kieran J., Litovchenko, Maria, Moskalev, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506837/
https://www.ncbi.nlm.nih.gov/pubmed/23090008
http://dx.doi.org/10.1007/s00109-012-0962-4