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Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases
Scientific understanding of the genetic components of aging has increased in recent years, with several genes being identified as playing roles in the aging process and, potentially, longevity. In particular, genes encoding components of the nuclear lamina in eukaryotes have been increasingly well c...
Autores principales: | Zhavoronkov, Alex, Smit-McBride, Zeljka, Guinan, Kieran J., Litovchenko, Maria, Moskalev, Alexey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506837/ https://www.ncbi.nlm.nih.gov/pubmed/23090008 http://dx.doi.org/10.1007/s00109-012-0962-4 |
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