Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis

INTRODUCTION: The current pathological confirmation of the diagnosis of Alzheimer's disease (AD) is still based on postmortem identification of parenchymal amyloid beta (Aβ) plaques, intra-neuronal neurofibrillary tangles, and neuronal loss. The memory deficits that are present in the early sta...

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Detalles Bibliográficos
Autores principales: Hanna, Amanda, Iremonger, Kayleigh, Das, Pritam, Dickson, Dennis, Golde, Todd, Janus, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506935/
https://www.ncbi.nlm.nih.gov/pubmed/22697412
http://dx.doi.org/10.1186/alzrt124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506935/
https://www.ncbi.nlm.nih.gov/pubmed/22697412
http://dx.doi.org/10.1186/alzrt124

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