Cargando…

Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis

INTRODUCTION: The current pathological confirmation of the diagnosis of Alzheimer's disease (AD) is still based on postmortem identification of parenchymal amyloid beta (Aβ) plaques, intra-neuronal neurofibrillary tangles, and neuronal loss. The memory deficits that are present in the early sta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hanna, Amanda, Iremonger, Kayleigh, Das, Pritam, Dickson, Dennis, Golde, Todd, Janus, Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506935/ https://www.ncbi.nlm.nih.gov/pubmed/22697412 http://dx.doi.org/10.1186/alzrt124

Ejemplares similares

Intracerebral but Not Peripheral Infection of Live Porphyromonas gingivalis Exacerbates Alzheimer’s Disease Like Amyloid Pathology in APP-TgCRND8 Mice
por: Aravindraja, Chairmandurai, et al.
Publicado: (2022)

Time course of focused ultrasound effects on β-amyloid plaque pathology in the TgCRND8 mouse model of Alzheimer’s disease
por: Poon, Charissa T., et al.
Publicado: (2018)

The Polyphenol Oleuropein Aglycone Protects TgCRND8 Mice against Aß Plaque Pathology
por: Grossi, Cristina, et al.
Publicado: (2013)

Antibodies Targeted to the Brain with Image-Guided Focused Ultrasound Reduces Amyloid-β Plaque Load in the TgCRND8 Mouse Model of Alzheimer's Disease
por: Jordão, Jessica F., et al.
Publicado: (2010)

Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo
por: Chakrabarty, Paramita, et al.
Publicado: (2011)

Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology
por: Das, Pritam, et al.
Publicado: (2012)

The Concentration of Soluble Extracellular Amyloid-β Protein in Acute Brain Slices from CRND8 Mice
por: Waters, Jack
Publicado: (2010)

Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition
por: Chakrabarty, Paramita, et al.
Publicado: (2012)

Proliferation, differentiation and amyloid-β production in neural progenitor cells isolated from TgCRND8 mice
por: Kanemoto, S., et al.
Publicado: (2014)

Sodium/myo-Inositol Transporters: Substrate Transport Requirements and Regional Brain Expression in the TgCRND8 Mouse Model of Amyloid Pathology
por: Fenili, Daniela, et al.
Publicado: (2011)

Normal cognition in transgenic BRI2-Aβ mice
por: Kim, Jungsu, et al.
Publicado: (2013)

The burden of amyloid light chain amyloidosis on health-related quality of life
por: Bayliss, Martha, et al.
Publicado: (2017)

Motor deficits are independent of axonopathy in an Alzheimer's disease mouse model of TgCRND8 mice
por: Yuan, Qiuju, et al.
Publicado: (2017)

Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo
por: Cao, Luxiang, et al.
Publicado: (2012)

Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer’s disease brains
por: Dudeffant, Clémence, et al.
Publicado: (2017)

Existing plaques and neuritic abnormalities in APP:PS1 mice are not affected by administration of the gamma-secretase inhibitor LY-411575
por: Garcia-Alloza, Monica, et al.
Publicado: (2009)

Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Aβ immunotherapy
por: Das, Pritam, et al.
Publicado: (2006)

Memory deficiency, cerebral amyloid angiopathy, and amyloid-β plaques in APP+PS1 double transgenic rat model of Alzheimer’s disease
por: Klakotskaia, Diana, et al.
Publicado: (2018)

Regional Amyloid Burden Differences Evaluated Using Quantitative Cardiac MRI in Patients with Cardiac Amyloidosis
por: Kim, Jin Young, et al.
Publicado: (2021)

S-Adenosylmethionine and Superoxide Dismutase 1 Synergistically Counteract Alzheimer’s Disease Features Progression in TgCRND8 Mice
por: Cavallaro, Rosaria A., et al.
Publicado: (2017)

Increased Heat Pain Tolerance but Hyperalgesia to Tonic Inflammatory Pain in the CRND8 Mouse Model of Alzheimer’s Disease
por: Merlo, Sara, et al.
Publicado: (2023)

Collagenous Alzheimer amyloid plaque component impacts on the compaction of amyloid-β plaques
por: Hashimoto, Tadafumi, et al.
Publicado: (2020)

Chronic Cladribine Administration Increases Amyloid Beta Peptide Generation and Plaque Burden in Mice
por: Hayes, Crystal D., et al.
Publicado: (2012)

Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease
por: Albuquerque, Marilia S., et al.
Publicado: (2015)

Different Patterns of Neurodegeneration and Glia Activation in CA1 and CA3 Hippocampal Regions of TgCRND8 Mice
por: Ugolini, Filippo, et al.
Publicado: (2018)

Differential contribution of APP metabolites to early cognitive deficits in a TgCRND8 mouse model of Alzheimer’s disease
por: Hamm, Valentine, et al.
Publicado: (2017)

A touch screen-automated cognitive test battery reveals impaired attention, memory abnormalities, and increased response inhibition in the TgCRND8 mouse model of Alzheimer's disease
por: Romberg, Carola, et al.
Publicado: (2013)

Amyloid A amyloidosis with subcutaneous drug abuse
por: Mendoza, Jair Munoz, et al.
Publicado: (2013)

Multiorgan involvement by amyloid light chain amyloidosis
por: Li, Guoliang, et al.
Publicado: (2019)

Dissection of the amyloid formation pathway in AL amyloidosis
por: Kazman, Pamina, et al.
Publicado: (2021)

Global epidemiology of amyloid light-chain amyloidosis
por: Kumar, Nishant, et al.
Publicado: (2022)

Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine
por: Hayes, Crystal D, et al.
Publicado: (2013)

Sleep-Wake Cycle Dysfunction in the TgCRND8 Mouse Model of Alzheimer’s Disease: From Early to Advanced Pathological Stages
por: Colby-Milley, Jessica, et al.
Publicado: (2015)

Successful Brain Delivery of Andrographolide Loaded in Human Albumin Nanoparticles to TgCRND8 Mice, an Alzheimer’s Disease Mouse Model
por: Bilia, Anna Rita, et al.
Publicado: (2019)

Grey zone amyloid burden affects memory function: the SCIENCe project
por: Ebenau, J. L., et al.
Publicado: (2020)

Nano-Honokiol ameliorates the cognitive deficits in TgCRND8 mice of Alzheimer’s disease via inhibiting neuropathology and modulating gut microbiota
por: Qu, Chang, et al.
Publicado: (2021)

Outcome of 121 patients with renal amyloid a amyloidosis
por: Ahbap, Elbis, et al.
Publicado: (2014)

Amyloid Goiter Associated with Amyloidosis Secondary to Rheumatoid Arthritis
por: Uzum, Gungor, et al.
Publicado: (2013)

Modified amyloid variants in pathological subgroups of β‐amyloidosis
por: Gerth, Janina, et al.
Publicado: (2018)

Quality of life assessment in amyloid transthyretin (ATTR) amyloidosis
por: Aimo, Alberto, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_43gma7252d1stnrj2v84lmrp2j