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Dystrophic neurites express C9orf72 in Alzheimer's disease brains

INTRODUCTION: Chromosome 9 open reading frame 72 (C9orf72) is an evolutionarily conserved protein with unknown function, expressed at high levels in the brain. An expanded hexanucleotide GGGGCC repeat located in the first intron of the C9orf72 gene represents the most common genetic cause of familia...

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Detalles Bibliográficos
Autores principales: Satoh, Jun-ichi, Tabunoki, Hiroko, Ishida, Tsuyoshi, Saito, Yuko, Arima, Kunimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506947/
https://www.ncbi.nlm.nih.gov/pubmed/22898310
http://dx.doi.org/10.1186/alzrt136