RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations

Predicting cellular responses to perturbations is an important task in systems biology. We report a new approach, RELATCH, which uses flux and gene expression data from a reference state to predict metabolic responses in a genetically or environmentally perturbed state. Using the concept of relative...

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Detalles Bibliográficos
Autores principales: Kim, Joonhoon, Reed, Jennifer L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506949/
https://www.ncbi.nlm.nih.gov/pubmed/23013597
http://dx.doi.org/10.1186/gb-2012-13-9-r78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506949/
https://www.ncbi.nlm.nih.gov/pubmed/23013597
http://dx.doi.org/10.1186/gb-2012-13-9-r78

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