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RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations
Predicting cellular responses to perturbations is an important task in systems biology. We report a new approach, RELATCH, which uses flux and gene expression data from a reference state to predict metabolic responses in a genetically or environmentally perturbed state. Using the concept of relative...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506949/ https://www.ncbi.nlm.nih.gov/pubmed/23013597 http://dx.doi.org/10.1186/gb-2012-13-9-r78 |