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Erlotinib eradicates brain metastases from epidermal growth factor receptor mutant non-small cell lung cancer

Erlotinib is active in patients with lung cancer; especially those who demonstrate a mutation in exons 18-21 in the epidermal growth factor receptor (EGFR) gene. Patients with lung cancer and brain metastases have poor prognosis as systemic chemotherapy is ineffective in treating the central nervous...

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Detalles Bibliográficos
Autores principales: Jabbari, Siavash, Pins, Michael, Kruczek, Kimberly, Nabhan, Chadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507060/
https://www.ncbi.nlm.nih.gov/pubmed/23210009
http://dx.doi.org/10.4103/2231-0770.90916