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Dual pathway spindle assembly increases both the speed and the fidelity of mitosis

Roughly half of all animal somatic cell spindles assemble by the classical prophase pathway, in which the centrosomes separate ahead of nuclear envelope breakdown (NEBD). The remainder assemble by the prometaphase pathway, in which the centrosomes separate following NEBD. Why cells use dual pathway...

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Detalles Bibliográficos
Autores principales: Kaseda, Kuniyoshi, McAinsh, Andrew D., Cross, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507165/
https://www.ncbi.nlm.nih.gov/pubmed/23213363
http://dx.doi.org/10.1242/bio.2011012