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Centrosome loss or amplification does not dramatically perturb global gene expression in Drosophila
Centrosome defects are a common feature of many cancers, and they can predispose fly brain cells to form tumours. In flies, centrosome defects perturb the asymmetric division of the neural stem cells, but it is unclear how this might lead to malignant transformation. One possibility is that centroso...
Autores principales: | Baumbach, Janina, Levesque, Mitchell P., Raff, Jordan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507170/ https://www.ncbi.nlm.nih.gov/pubmed/23213376 http://dx.doi.org/10.1242/bio.20122238 |
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