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The interrelationship between APC/C and Plk1 activities in centriole disengagement

Mother–daughter centriole disengagement, the necessary first step in centriole duplication, involves Plk1 activity in early mitosis and separase activity after APC/C activity mediates securin degradation. Plk1 activity is thought to be essential and sufficient for centriole disengagement with separa...

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Detalles Bibliográficos
Autores principales: Hatano, Toshiyuki, Sluder, Greenfield
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507193/
https://www.ncbi.nlm.nih.gov/pubmed/23213396
http://dx.doi.org/10.1242/bio.20122626