The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A

The cullin-RING family of ubiquitin ligases regulates diverse cellular functions, such as cell cycle control, via ubiquitylation of specific substrates. CUL3 targets its substrates through BTB proteins. Here we show that depletion of CUL3 and the BTB protein KLHL18 causes a delay in mitotic entry. C...

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Detalles Bibliográficos
Autores principales: Moghe, Saili, Jiang, Fei, Miura, Yoshie, Cerny, Ronald L., Tsai, Ming-Ying, Furukawa, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507203/
https://www.ncbi.nlm.nih.gov/pubmed/23213400
http://dx.doi.org/10.1242/bio.2011018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507203/
https://www.ncbi.nlm.nih.gov/pubmed/23213400
http://dx.doi.org/10.1242/bio.2011018

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