The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs

The membrane-anchored metalloproteinase-regulator RECK has been characterized as a tumor suppressor. Here we report that mice with reduced Reck-expression show limb abnormalities including right-dominant, forelimb-specific defects in postaxial skeletal elements. The forelimb buds of low-Reck mutants...

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Detalles Bibliográficos
Autores principales: Yamamoto, Mako, Matsuzaki, Tomoko, Takahashi, Rei, Adachi, Eijiro, Maeda, Yasuhiro, Yamaguchi, Sachiyo, Kitayama, Hitoshi, Echizenya, Michiko, Morioka, Yoko, Alexander, David B., Yagi, Takeshi, Itohara, Shigeyoshi, Nakamura, Takashi, Akiyama, Haruhiko, Noda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507216/
https://www.ncbi.nlm.nih.gov/pubmed/23213437
http://dx.doi.org/10.1242/bio.2012638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507216/
https://www.ncbi.nlm.nih.gov/pubmed/23213437
http://dx.doi.org/10.1242/bio.2012638

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