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Simulations demonstrate a simple network to be sufficient to control branch point selection, smooth muscle and vasculature formation during lung branching morphogenesis

Proper lung functioning requires not only a correct structure of the conducting airway tree, but also the simultaneous development of smooth muscles and vasculature. Lung branching morphogenesis is strongly stereotyped and involves the recursive use of only three modes of branching. We have previous...

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Detalles Bibliográficos
Autores principales: Cellière, Géraldine, Menshykau, Denis, Iber, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507219/
https://www.ncbi.nlm.nih.gov/pubmed/23213471
http://dx.doi.org/10.1242/bio.20121339