Cargando…

A growth factor signaling cascade confined to circular ruffles in macrophages

The formation of macropinosomes requires large-scale movements of membranes and the actin cytoskeleton. Over several minutes, actin-rich surface ruffles transform into 1–5 µm diameter circular ruffles, which close at their distal margins, creating endocytic vesicles. Previous studies using fluoresce...

Descripción completa

Detalles Bibliográficos
Autores principales: Welliver, Timothy P., Swanson, Joel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507227/
https://www.ncbi.nlm.nih.gov/pubmed/23213469
http://dx.doi.org/10.1242/bio.20121784