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TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal protein S6 in fission yeast

TOR (Target Of Rapamycin) signalling coordinates cell growth and division in response to changes in the nutritional environment of the cell. TOR kinases form two distinct complexes: TORC1 and TORC2. In mammals, the TORC1 controlled S6K1 kinase phosphorylates the ribosomal protein S6 thereby co-ordin...

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Detalles Bibliográficos
Autores principales: Du, Wei, Hálová, Lenka, Kirkham, Sara, Atkin, Jane, Petersen, Janni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507231/
https://www.ncbi.nlm.nih.gov/pubmed/23213482
http://dx.doi.org/10.1242/bio.20122022