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Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis

Axial mesendoderm is comprised of prechordal plate and notochord. Lack of a suitable Cre driver has hampered the ability to genetically dissect the requirement for each of these components, or genes expressed within them, to anterior patterning. Here, we have utilized Isl1-Cre to investigate roles o...

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Detalles Bibliográficos
Autores principales: Harrelson, Zachary, Kaestner, Klaus H., Evans, Sylvia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507292/
https://www.ncbi.nlm.nih.gov/pubmed/23213408
http://dx.doi.org/10.1242/bio.2012040