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DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network

During DNA replication, stalled replication forks and DSBs arise when the replication fork encounters ICLs (interstrand crosslinks), covalent protein/DNA intermediates or other discontinuities in the template. Recently, homologous recombination proteins have been shown to function in replication-cou...

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Detalles Bibliográficos
Autores principales: Karanja, Kenneth K., Cox, Stephanie W., Duxin, Julien P., Stewart, Sheila A., Campbell, Judith L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507494/
https://www.ncbi.nlm.nih.gov/pubmed/22987153
http://dx.doi.org/10.4161/cc.22215