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Metformin and the Risk of Cancer: Time-related biases in observational studies
OBJECTIVE: Time-related biases in observational studies of drug effects have been described extensively in different therapeutic areas but less so in diabetes. Immortal time bias, time-window bias, and time-lag bias all tend to greatly exaggerate the benefits observed with a drug. RESEARCH DESIGN AN...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Diabetes Association
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507580/ https://www.ncbi.nlm.nih.gov/pubmed/23173135 http://dx.doi.org/10.2337/dc12-0788 |