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Metformin and the Risk of Cancer: Time-related biases in observational studies

OBJECTIVE: Time-related biases in observational studies of drug effects have been described extensively in different therapeutic areas but less so in diabetes. Immortal time bias, time-window bias, and time-lag bias all tend to greatly exaggerate the benefits observed with a drug. RESEARCH DESIGN AN...

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Detalles Bibliográficos
Autores principales:	Suissa, Samy, Azoulay, Laurent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507580/ https://www.ncbi.nlm.nih.gov/pubmed/23173135 http://dx.doi.org/10.2337/dc12-0788

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