ABC Transporter Genes and Risk of Type 2 Diabetes: A study of 40,000 individuals from the general population

OBJECTIVE: Alterations of pancreatic β-cell cholesterol content may contribute to β-cell dysfunction. Two important determinants of intracellular cholesterol content are the ATP-binding cassette (ABC) transporters A1 (ABCA1) and -G1 (ABCG1). Whether genetic variation in ABCA1 and ABCG1 predicts risk...

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Detalles Bibliográficos
Autores principales: Schou, Jesper, Tybjærg-Hansen, Anne, Møller, Holger J., Nordestgaard, Børge G., Frikke-Schmidt, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507608/
https://www.ncbi.nlm.nih.gov/pubmed/23139370
http://dx.doi.org/10.2337/dc12-0082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507608/
https://www.ncbi.nlm.nih.gov/pubmed/23139370
http://dx.doi.org/10.2337/dc12-0082

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