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Dose-dependent effects of small-molecule antagonists on the genomic landscape of androgen receptor binding
BACKGROUND: The androgen receptor plays a critical role throughout the progression of prostate cancer and is an important drug target for this disease. While chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-Seq) is becoming an essential tool for studying transcription a...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507642/ https://www.ncbi.nlm.nih.gov/pubmed/22849360 http://dx.doi.org/10.1186/1471-2164-13-355 |