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A new look at an old virus: patterns of mutation accumulation in the human H1N1 influenza virus since 1918
BACKGROUND: The H1N1 influenza A virus has been circulating in the human population for over 95 years, first manifesting itself in the pandemic of 1917–1918. Initial mortality was extremely high, but dropped exponentially over time. Influenza viruses have high mutation rates, and H1N1 has undergone...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507676/ https://www.ncbi.nlm.nih.gov/pubmed/23062055 http://dx.doi.org/10.1186/1742-4682-9-42 |