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Zinc Transporter 8 (ZnT8) Expression Is Reduced by Ischemic Insults: A Potential Therapeutic Target to Prevent Ischemic Retinopathy

The zinc (Zn(++)) transporter ZnT8 plays a crucial role in zinc homeostasis. It’s been reported that an acute decrease in ZnT8 levels impairs β cell function and Zn(++) homeostasis, which contribute to the pathophysiology of diabetes mellitus (DM). Although ZnT8 expression has been detected in the r...

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Detalles Bibliográficos
Autores principales: DeNiro, Michael, Al-Mohanna, Futwan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507680/
https://www.ncbi.nlm.nih.gov/pubmed/23209723
http://dx.doi.org/10.1371/journal.pone.0050360