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Generation of an Rx-tTA: TetOp-Cre Knock-In Mouse Line for Doxycycline Regulated Cre Activity in the Rx Expression Domain

Genetic deletion of mouse genes has played a crucial role in our understanding of embryonic eye development. Transgenic, tissue specific Cre recombinase expression in various eye structures has facilitated these experiments. However, an early expressing, temporally-regulated, optic vesicle-specific...

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Detalles Bibliográficos
Autores principales: Plageman, Timothy F., Lang, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507682/
https://www.ncbi.nlm.nih.gov/pubmed/23209739
http://dx.doi.org/10.1371/journal.pone.0050426