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Generation of an Rx-tTA: TetOp-Cre Knock-In Mouse Line for Doxycycline Regulated Cre Activity in the Rx Expression Domain
Genetic deletion of mouse genes has played a crucial role in our understanding of embryonic eye development. Transgenic, tissue specific Cre recombinase expression in various eye structures has facilitated these experiments. However, an early expressing, temporally-regulated, optic vesicle-specific...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507682/ https://www.ncbi.nlm.nih.gov/pubmed/23209739 http://dx.doi.org/10.1371/journal.pone.0050426 |