Crystal Structure of the Hexachlorocyclohexane Dehydrochlorinase (LinA-Type2): Mutational Analysis, Thermostability and Enantioselectivity

Hexachlorocyclohexane dehydrochlorinase (LinA) mediates dehydrochlorination of γ-HCH to 1, 3, 4, 6-tetrachloro-1,4-cyclohexadiene that constitutes first step of the aerobic degradation pathway. We report the 3.5 Å crystal structure of a thermostable LinA-type2 protein, obtained from a soil metagenom...

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Detalles Bibliográficos
Autores principales: Macwan, Ankit S., Kukshal, Vandna, Srivastava, Nidhi, Javed, Saleem, Kumar, Ashwani, Ramachandran, Ravishankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507683/
https://www.ncbi.nlm.nih.gov/pubmed/23209726
http://dx.doi.org/10.1371/journal.pone.0050373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507683/
https://www.ncbi.nlm.nih.gov/pubmed/23209726
http://dx.doi.org/10.1371/journal.pone.0050373

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