A Single Glycine-Alanine Exchange Directs Ligand Specificity of the Elephant Progestin Receptor

The primary gestagen of elephants is 5α-dihydroprogesterone (DHP), which is unlike all other mammals studied until now. The level of DHP in elephants equals that of progesterone in other mammals, and elephants are able to bind DHP with similar affinity to progesterone indicating a unique ligand-bind...

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Detalles Bibliográficos
Autores principales: Wierer, Michael, Schrey, Anna K., Kühne, Ronald, Ulbrich, Susanne E., Meyer, Heinrich H. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507690/
https://www.ncbi.nlm.nih.gov/pubmed/23209719
http://dx.doi.org/10.1371/journal.pone.0050350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507690/
https://www.ncbi.nlm.nih.gov/pubmed/23209719
http://dx.doi.org/10.1371/journal.pone.0050350

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