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A Single Glycine-Alanine Exchange Directs Ligand Specificity of the Elephant Progestin Receptor
The primary gestagen of elephants is 5α-dihydroprogesterone (DHP), which is unlike all other mammals studied until now. The level of DHP in elephants equals that of progesterone in other mammals, and elephants are able to bind DHP with similar affinity to progesterone indicating a unique ligand-bind...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507690/ https://www.ncbi.nlm.nih.gov/pubmed/23209719 http://dx.doi.org/10.1371/journal.pone.0050350 |