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Impaired c-Fos and Polo-Like Kinase 2 Induction in the Limbic System of Fear-conditioned α-Synuclein Transgenic Mice

α-Synuclein (αSYN) is genetically and neuropathologically linked to a spectrum of neurodegenerative diseases including Parkinson’s disease, dementia with Lewy bodies, and related disorders. Cognitive impairment is recapitulated in several αSYN transgenic mouse lines. However, the mechanisms of dysfu...

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Detalles Bibliográficos
Autores principales: Schell, Heinrich, Boden, Cindy, Chagas, André Maia, Kahle, Philipp J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507699/
https://www.ncbi.nlm.nih.gov/pubmed/23209687
http://dx.doi.org/10.1371/journal.pone.0050245