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Immunogenicity of Bivalent Human Papillomavirus DNA Vaccine Using Human Endogenous Retrovirus Envelope-Coated Baculoviral Vectors in Mice and Pigs

Human papillomavirus is known to be the major pathogen of cervical cancer. Here, we report the efficacy of a bivalent human papillomavirus type 16 and 18 DNA vaccine system following repeated dosing in mice and pigs using a recombinant baculovirus bearing human endogenous retrovirus envelope protein...

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Detalles Bibliográficos
Autores principales: Lee, Hee-Jung, Hur, Yoon-Ki, Cho, Youn-Dong, Kim, Mi-Gyeong, Lee, Hoon-Taek, Oh, Yu-Kyoung, Kim, Young Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507738/
https://www.ncbi.nlm.nih.gov/pubmed/23209698
http://dx.doi.org/10.1371/journal.pone.0050296