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Influence of Genetic Variants in Type I Interferon Genes on Melanoma Survival and Therapy

Melanoma is an immunogenic tumor; however, the efficacy of immune-therapy shows large inter-individual variation with possible influence of background genetic variation. In this study we report the influence of genetic polymorphisms in the type I interferon gene cluster on chromosome 9p22 on melanom...

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Detalles Bibliográficos
Autores principales: Lenci, Romina Elizabeth, Bevier, Melanie, Brandt, Andreas, Bermejo, Justo Lorenzo, Sucker, Antje, Moll, Iris, Planelles, Dolores, Requena, Celia, Nagore, Eduardo, Hemminki, Kari, Schadendorf, Dirk, Kumar, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507747/
https://www.ncbi.nlm.nih.gov/pubmed/23209811
http://dx.doi.org/10.1371/journal.pone.0050692