Pharmacokinetic and -dynamic modelling of G-CSF derivatives in humans

BACKGROUND: The human granulocyte colony-stimulating factor (G-CSF) is routinely applied to support recovery of granulopoiesis during the course of cytotoxic chemotherapies. However, optimal use of the drug is largely unknown. We showed in the past that a biomathematical compartment model of human g...

Descripción completa

Detalles Bibliográficos
Autores principales: Scholz, Markus, Schirm, Sibylle, Wetzler, Marcus, Engel, Christoph, Loeffler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507764/
https://www.ncbi.nlm.nih.gov/pubmed/22846180
http://dx.doi.org/10.1186/1742-4682-9-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507764/
https://www.ncbi.nlm.nih.gov/pubmed/22846180
http://dx.doi.org/10.1186/1742-4682-9-32

Ejemplares similares