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Pharmacokinetic and -dynamic modelling of G-CSF derivatives in humans
BACKGROUND: The human granulocyte colony-stimulating factor (G-CSF) is routinely applied to support recovery of granulopoiesis during the course of cytotoxic chemotherapies. However, optimal use of the drug is largely unknown. We showed in the past that a biomathematical compartment model of human g...
Autores principales: | Scholz, Markus, Schirm, Sibylle, Wetzler, Marcus, Engel, Christoph, Loeffler, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507764/ https://www.ncbi.nlm.nih.gov/pubmed/22846180 http://dx.doi.org/10.1186/1742-4682-9-32 |
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