Enterohemorrhagic Escherichia coli Specific Enterohemolysin Induced IL-1β in Human Macrophages and EHEC-Induced IL-1β Required Activation of NLRP3 Inflammasome

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a major foodborne pathogen causing hemorrhagic colitis and hemolytic-uremic syndrome. The role of EHEC O157:H7-enterohemolysin (Ehx) in the pathogenesis of infections remains poorly defined. In this study, we used gene deletion and complement meth...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoai, Cheng, Yuli, Xiong, Yanwen, Ye, Changyun, Zheng, Han, Sun, Hui, Zhao, Hongqing, Ren, Zhihong, Xu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507778/
https://www.ncbi.nlm.nih.gov/pubmed/23209696
http://dx.doi.org/10.1371/journal.pone.0050288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507778/
https://www.ncbi.nlm.nih.gov/pubmed/23209696
http://dx.doi.org/10.1371/journal.pone.0050288

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