Cargando…

MSH3-Deficiency Initiates EMAST without Oncogenic Transformation of Human Colon Epithelial Cells

BACKGROUND/AIM: Elevated microsatellite instability at selected tetranucleotide repeats (EMAST) is a genetic signature in certain cases of sporadic colorectal cancer and has been linked to MSH3-deficiency. It is currently controversial whether EMAST is associated with oncogenic properties in humans,...

Descripción completa

Detalles Bibliográficos
Autores principales: Campregher, Christoph, Schmid, Gerald, Ferk, Franziska, Knasmüller, Siegfried, Khare, Vineeta, Kortüm, Benedikt, Dammann, Kyle, Lang, Michaela, Scharl, Theresa, Spittler, Andreas, Roig, Andres I., Shay, Jerry W., Gerner, Christopher, Gasche, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507781/
https://www.ncbi.nlm.nih.gov/pubmed/23209772
http://dx.doi.org/10.1371/journal.pone.0050541