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MSH3-Deficiency Initiates EMAST without Oncogenic Transformation of Human Colon Epithelial Cells
BACKGROUND/AIM: Elevated microsatellite instability at selected tetranucleotide repeats (EMAST) is a genetic signature in certain cases of sporadic colorectal cancer and has been linked to MSH3-deficiency. It is currently controversial whether EMAST is associated with oncogenic properties in humans,...
Autores principales: | Campregher, Christoph, Schmid, Gerald, Ferk, Franziska, Knasmüller, Siegfried, Khare, Vineeta, Kortüm, Benedikt, Dammann, Kyle, Lang, Michaela, Scharl, Theresa, Spittler, Andreas, Roig, Andres I., Shay, Jerry W., Gerner, Christopher, Gasche, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507781/ https://www.ncbi.nlm.nih.gov/pubmed/23209772 http://dx.doi.org/10.1371/journal.pone.0050541 |
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