HUWE1 and TRIP12 Collaborate in Degradation of Ubiquitin-Fusion Proteins and Misframed Ubiquitin

In eukaryotic cells an uncleavable ubiquitin moiety conjugated to the N-terminus of a protein signals the degradation of the fusion protein via the proteasome-dependent ubiquitin fusion degradation (UFD) pathway. In yeast the molecular mechanism of the UFD pathway has been well characterized. Recent...

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Detalles Bibliográficos
Autores principales: Poulsen, Esben G., Steinhauer, Cornelia, Lees, Michael, Lauridsen, Anne-Marie, Ellgaard, Lars, Hartmann-Petersen, Rasmus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507821/
https://www.ncbi.nlm.nih.gov/pubmed/23209776
http://dx.doi.org/10.1371/journal.pone.0050548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507821/
https://www.ncbi.nlm.nih.gov/pubmed/23209776
http://dx.doi.org/10.1371/journal.pone.0050548

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