Proof of Concept: Matrix metalloproteinase inhibitor decreases inflammation and improves muscle insulin sensitivity in people with type 2 diabetes

BACKGROUND: Obesity is a state of subclinical inflammation resulting in loss of function of insulin receptors and decreased insulin sensitivity. Inhibition of the inflammatory enzymes, matrix metalloproteinases (MMPs), for 6 months in rodent models restores insulin receptor function and insulin sens...

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Detalles Bibliográficos
Autores principales: Frankwich, Karen, Tibble, Courtney, Torres-Gonzalez, Moises, Bonner, Mariah, Lefkowitz, Roy, Tyndall, Matt, Schmid-Schönbein, Geert W, Villarreal, Francisco, Heller, Mike, Herbst, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507843/
https://www.ncbi.nlm.nih.gov/pubmed/23025537
http://dx.doi.org/10.1186/1476-9255-9-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507843/
https://www.ncbi.nlm.nih.gov/pubmed/23025537
http://dx.doi.org/10.1186/1476-9255-9-35

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