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In vitro silencing of the insulin receptor attenuates cellular accumulation of fibronectin in renal mesangial cells
BACKGROUND: Insulin receptor (InsR) and insulin signaling proteins are widely distributed throughout the kidney cortex. Insulin signaling can act in the kidney in multiple ways, some of which may be totally independent of its primary role of the maintenance of whole-body glucose homeostasis. However...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507851/ https://www.ncbi.nlm.nih.gov/pubmed/23061721 http://dx.doi.org/10.1186/1478-811X-10-29 |