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In vitro silencing of the insulin receptor attenuates cellular accumulation of fibronectin in renal mesangial cells

BACKGROUND: Insulin receptor (InsR) and insulin signaling proteins are widely distributed throughout the kidney cortex. Insulin signaling can act in the kidney in multiple ways, some of which may be totally independent of its primary role of the maintenance of whole-body glucose homeostasis. However...

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Detalles Bibliográficos
Autores principales:	Yano, Naohiro, Suzuki, Daisuke, Endoh, Masayuki, Zhang, Weizhi, Xu, Yan Chun, Padbury, James F, Tseng, Yi-Tang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507851/ https://www.ncbi.nlm.nih.gov/pubmed/23061721 http://dx.doi.org/10.1186/1478-811X-10-29

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