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Lack of p53 Affects the Expression of Several Brain Mitochondrial Proteins: Insights from Proteomics into Important Pathways Regulated by p53

The tumor suppressor protein p53 has been described “as the guardian of the genome” for its crucial role in regulating the transcription of numerous genes responsible for cells cycle arrest, senescence, or apoptosis in response to various stress signals. Although p53 promotes longevity by decreasing...

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Detalles Bibliográficos
Autores principales: Fiorini, Ada, Sultana, Rukhsana, Barone, Eugenio, Cenini, Giovanna, Perluigi, Marzia, Mancuso, Cesare, Cai, Jian, Klein, Jon B., St. Clair, Daret, Butterfield, D. Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507874/
https://www.ncbi.nlm.nih.gov/pubmed/23209608
http://dx.doi.org/10.1371/journal.pone.0049846