Transcriptome Profiling of Peripheral Blood Cells Identifies Potential Biomarkers for Doxorubicin Cardiotoxicity in a Rat Model

AIMS: Doxorubicin (DOX), a widely used anticancer agent, can cause an unpredictable cardiac toxicity which remains a major limitation in cancer chemotherapy. There is a need for noninvasive, sensitive and specific biomarkers which will allow identifying patients at risk for DOX-induced cardiotoxicit...

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Detalles Bibliográficos
Autores principales: Todorova, Valentina K., Beggs, Marjorie L., Delongchamp, Robert R., Dhakal, Ishwori, Makhoul, Issam, Wei, Jeanne Y., Klimberg, V. Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507887/
https://www.ncbi.nlm.nih.gov/pubmed/23209553
http://dx.doi.org/10.1371/journal.pone.0048398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507887/
https://www.ncbi.nlm.nih.gov/pubmed/23209553
http://dx.doi.org/10.1371/journal.pone.0048398

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