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Antiproliferative Effects of Fluoxetine on Colon Cancer Cells and in a Colonic Carcinogen Mouse Model

The antidepressant fluoxetine has been under discussion because of its potential influence on cancer risk. It was found to inhibit the development of carcinogen-induced preneoplastic lesions in colon tissue, but the mechanisms of action are not well understood. Therefore, we investigated anti-prolif...

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Detalles Bibliográficos
Autores principales: Kannen, Vinicius, Hintzsche, Henning, Zanette, Dalila L., Silva, Wilson A., Garcia, Sérgio B., Waaga-Gasser, Ana Maria, Stopper, Helga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507893/
https://www.ncbi.nlm.nih.gov/pubmed/23209640
http://dx.doi.org/10.1371/journal.pone.0050043