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Antiproliferative Effects of Fluoxetine on Colon Cancer Cells and in a Colonic Carcinogen Mouse Model
The antidepressant fluoxetine has been under discussion because of its potential influence on cancer risk. It was found to inhibit the development of carcinogen-induced preneoplastic lesions in colon tissue, but the mechanisms of action are not well understood. Therefore, we investigated anti-prolif...
Autores principales: | Kannen, Vinicius, Hintzsche, Henning, Zanette, Dalila L., Silva, Wilson A., Garcia, Sérgio B., Waaga-Gasser, Ana Maria, Stopper, Helga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507893/ https://www.ncbi.nlm.nih.gov/pubmed/23209640 http://dx.doi.org/10.1371/journal.pone.0050043 |
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